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E2F6 Antibody
SKU / CAT#: V9188-100UG
$49900
usd
$4.99/UG
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V9188-100UG

E2F6 Antibody

NSJ Bioreagents
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SKU / CAT#: V9188-100UG
MPN: V9188-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
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Description
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding...
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the E2F6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This E2F6 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
eaqSQe2f6-antibody-pcrp-e2f6-1f8-v9188
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
O75461
CLONE NUMBER
PCRP-E2F6-1F8
*USAGE / SAFETY STATEMENT
This E2F6 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human E2F6 protein was used as the immunogen for the E2F6 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the E2F6 antibody should be determined by the researcher.
LOCALIZATION
Nucleus
Questions & Answers (0)
Citations (0)
Immunofluorescent staining of human HeLa cells using E2F6 antibody (green, clone PCRP-E2F6-1F8) and phalloidin (red).
Immunofluorescent staining of human HeLa cells using E2F6 antibody (green, clone PCRP-E2F6-1F8) and phalloidin (red).
FACS staining of PFA-fixed human HeLa cells with E2F6 antibody (blue, clone PCRP-E2F6-1F8), and unstained cells (red).
+1
SDS-PAGE analysis of purified, BSA-free E2F6 antibody (PCRP-E2F6-1F8) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the E2F6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This E2F6 antibody is available for research use only.
Regulatory & Compliance
Badge
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