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Perforin Antibody / PRF1
SKU / CAT#: V9142SAF-100UG
$49900
usd
$4.99/UG
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V9142SAF-100UG

Perforin Antibody / PRF1

NSJ Bioreagents
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SKU / CAT#: V9142SAF-100UG
MPN: V9142SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
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Description
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis...
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis...
Shipping & Handling
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Safety & Storage
Storage Temperature
Aliquot the Perforin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Perforin antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
DoTOqperforin-antibody-spm434-v9142
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P14222
CLONE NUMBER
SPM434
*USAGE / SAFETY STATEMENT
This Perforin antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
ELISA
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
A portion of amino acids 413-552 was used as the immunogen for the Perforin antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
ELISA: 1-5ug/ml (order BSA-free format for coating)
APPLICATION NOTES
Optimal dilution of the Perforin antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic
Questions & Answers (0)
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Perforin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Perforin antibody is available for research use only.
Regulatory & Compliance
Badge
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