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Bcl10 Antibody
SKU / CAT#: V9102-20UG
$21900
usd
$10.95/UG
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V9102-20UG

Bcl10 Antibody

NSJ Bioreagents
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SKU / CAT#: V9102-20UG
MPN: V9102-20UG
$21900
usd
$10.95/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
Bcl10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of Bcl10 was shown to induce NF-kB activation in a NIK-dependent pathway. This mAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower...
Bcl10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of Bcl10 was shown to induce NF-kB activation in a NIK-dependent pathway. This mAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Bcl10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Bcl10 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
wWaQubcl10-antibody-spm520-v9102
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
O95999
CLONE NUMBER
SPM520
*USAGE / SAFETY STATEMENT
This Bcl10 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Amino acids 122-168 were used as the immunogen for this Bcl10 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1) (2)
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
LOCALIZATION
Nuclear and cytoplasmic
Questions & Answers (0)
Citations (0)
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with Bcl10 antibody (SPM520).
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with Bcl10 antibody (SPM520).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Bcl10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Bcl10 antibody is available for research use only.
Regulatory & Compliance
Badge
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