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C4d / Complement 4d Antibody
SKU / CAT#: V9091SAF-100UG
$49900
usd
$4.99/UG
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V9091SAF-100UG

C4d / Complement 4d Antibody

NSJ Bioreagents
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SKU / CAT#: V9091SAF-100UG
MPN: V9091SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
SKU
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Description
This mAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries...
This mAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Complement 4d antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Complement 4d antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
GZudZcomplement-4d-antibody-spm545-v9091
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P0C0L4, P0C0L5
CLONE NUMBER
SPM545
*USAGE / SAFETY STATEMENT
This Complement 4d antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Recombinant human C4d protein was used as the immunogen for this Complement 4d antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1:200-1:400 for 30 min at RT
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
LOCALIZATION
Intracytoplasmic vacuoles of endothelial cells, secreted
Questions & Answers (0)
Citations (0)
IHC testing of FFPE human kidney transplant with Complement 4d antibody (SPM545). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.
IHC testing of FFPE human kidney transplant with Complement 4d antibody (SPM545). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Complement 4d antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Complement 4d antibody is available for research use only.
Regulatory & Compliance
Badge
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