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CD16 Antibody
SKU / CAT#: V8858-100UG
$49900
usd
$4.99/UG
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V8858-100UG

CD16 Antibody

NSJ Bioreagents
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SKU / CAT#: V8858-100UG
MPN: V8858-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
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Description
It recognizes CD16 (Fc gamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fc gamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and...
It recognizes CD16 (Fc gamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fc gamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the CD16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This CD16 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
SCyVdcd16-antibody-c16-1045-v8858
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P08637
CLONE NUMBER
C16/1045
*USAGE / SAFETY STATEMENT
This CD16 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant human CD16 protein was used as the immunogen for the CD16 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the CD16 antibody should be determined by the researcher.
LOCALIZATION
Cell Surface
Questions & Answers (0)
Citations (0)
FACS staining of lymphocyte-gated human PBM cells with CD16 antibody (violet, clone C16/1045), and unstained cells (gray).
FACS staining of lymphocyte-gated human PBM cells with CD16 antibody (violet, clone C16/1045), and unstained cells (gray).
SDS-PAGE analysis of purified, BSA-free CD16 antibody (clone C16/1045) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the CD16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This CD16 antibody is available for research use only.
Regulatory & Compliance
Badge
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