ALK Antibody / Anaplastic Lymphoma Kinase
SKU / CAT#: V8812-20UG
$21900
usd$10.95/UG
ALK Antibody / Anaplastic Lymphoma Kinase
NSJ BioreagentsSKU / CAT#: V8812-20UG
MPN: V8812-20UG
$21900
usd$10.95/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
The wild-type anaplastic lymphoma kinase (ALK) protein is a 200kDa transmembrane receptor tyrosine kinase. Its expression is restricted to a few scattered cells in the nervous system (some glial cells and neurons, and a few endothelial cells and pericytes. The hybrid gene,NPM-ALK, created by the t(2;5)(p23;q35) chromosomal translocation encodes part of the nucleolar phosphoprotein, nucleophosmin (NPM), joined to the entire cytoplasmic portion of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. As a consequence, the ALK gene comes under the control of the NPM promoter, which induces...
The wild-type anaplastic lymphoma kinase (ALK) protein is a 200kDa transmembrane receptor tyrosine kinase. Its expression is restricted to a few scattered cells in the nervous system (some glial cells and neurons, and a few endothelial cells and pericytes. The hybrid gene,NPM-ALK, created by the t(2;5)(p23;q35) chromosomal translocation encodes part of the nucleolar phosphoprotein, nucleophosmin (NPM), joined to the entire cytoplasmic portion of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. As a consequence, the ALK gene comes under the control of the NPM promoter, which induces...
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Safety & Storage
Storage Temperature
Aliquot the Anaplastic Lymphoma Kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Anaplastic Lymphoma Kinase antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q9UM73CLONE NUMBER
ALK/1032
*USAGE / SAFETY STATEMENT
This Anaplastic Lymphoma Kinase antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
A portion of amino acids 220-335 was used as the immunogen for the Anaplastic Lymphoma Kinase antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Western blot: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the Anaplastic Lymphoma Kinase antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic, Nuclear
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Anaplastic Lymphoma Kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Anaplastic Lymphoma Kinase antibody is available for research use only.
Regulatory & Compliance
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