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EGF Receptor / EGFR Antibody-L858R Mutant Specific
SKU / CAT#: V8746-20UG
$21900
usd
$10.95/UG
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  4. EGF Receptor / EGFR Antibody-L858R Mutant Specific
V8746-20UG

EGF Receptor / EGFR Antibody-L858R Mutant Specific

NSJ Bioreagents
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SKU / CAT#: V8746-20UG
MPN: V8746-20UG
$21900
usd
$10.95/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
SKU
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Description
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades...
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant EGFR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant EGFR antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
lFzenrecombinant-egfr-antibody-gfr-4564r-v8746
Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
P00533
CLONE NUMBER
GFR/4564R
*USAGE / SAFETY STATEMENT
This recombinant EGFR antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A affinity chromatography
IMMUNOGEN
A portion of amino acids 800-900 of EGF receptor (mutated L858R) was used as the immunogen for the recombinant EGFR antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the recombinant EGFR antibody should be determined by the researcher.
LOCALIZATION
Cytomembrane
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human placenta with recombinant EGFR antibody (clone GFR/4564R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human placenta with recombinant EGFR antibody (clone GFR/4564R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human placenta with recombinant EGFR antibody (clone GFR/4564R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant EGFR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant EGFR antibody is available for research use only.
Regulatory & Compliance
Badge
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