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B7-H6 Antibody / NCR3LG1
SKU / CAT#: V8734SAF-100UG
$49900
usd
$4.99/UG
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V8734SAF-100UG

B7-H6 Antibody / NCR3LG1

NSJ Bioreagents
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SKU / CAT#: V8734SAF-100UG
MPN: V8734SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 4th
Available
SHIPS Jul 4th
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Description
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the B7-H6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This B7-H6 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
oCbMwb7-h6-antibody-b7h6-4821-v8734
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q68D85
CLONE NUMBER
B7H6/4821
*USAGE / SAFETY STATEMENT
This B7-H6 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A portion of amino acids 38-169 from the human protein was used as the immunogen for the B7-H6 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the B7-H6 antibody should be determined by the researcher.
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human tonsil with B7-H6 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human tonsil with B7-H6 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human liver carcinoma with B7-H6 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the B7-H6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This B7-H6 antibody is available for research use only.
Regulatory & Compliance
Badge
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