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Steroidogenic Factor 1 Antibody / SF-1 / NR5A1
SKU / CAT#: V8731-100UG
$49900
usd
$4.99/UG
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V8731-100UG

Steroidogenic Factor 1 Antibody / SF-1 / NR5A1

NSJ Bioreagents
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SKU / CAT#: V8731-100UG
MPN: V8731-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the NR5A1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This NR5A1 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
uYZEAnr5a1-antibody-nr5a1-3397-v8731
Specifications
HOST SPECIES
Mouse
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q13285
CLONE NUMBER
NR5A1/3397
*USAGE / SAFETY STATEMENT
This NR5A1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A portion of amino acids 220-461 from the human protein was used as the immunogen for the NR5A1 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the NR5A1 antibody should be determined by the researcher.
LOCALIZATION
Nuclear
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human thymus with NR5A1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human thymus with NR5A1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human testis with NR5A1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using NR5A1 antibody. These results demonstrate the foremost specificity of the NR5A1/3397 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the NR5A1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This NR5A1 antibody is available for research use only.
Regulatory & Compliance
Badge
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