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TTR Antibody / Transthyretin / Prealbumin
SKU / CAT#: V8720SAF-100UG
$49900
usd
$4.99/UG
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V8720SAF-100UG

TTR Antibody / Transthyretin / Prealbumin

NSJ Bioreagents
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SKU / CAT#: V8720SAF-100UG
MPN: V8720SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic...
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Transthyretin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Transthyretin antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
jFraYtransthyretin-antibody-ttr-4296-v8720
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P02766
CLONE NUMBER
TTR/4296
*USAGE / SAFETY STATEMENT
This Transthyretin antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P, WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Recombinant human full-length protein was used as the immunogen for the Transthyretin antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Western blot: 2-4ug/ml
APPLICATION NOTES
Optimal dilution of the Transthyretin antibody should be determined by the researcher.
LOCALIZATION
Secreted, cytoplasm
Questions & Answers (0)
Citations (0)
Western blot testing of human liver lysate with Transthyretin antibody. Predicted molecular weight ~16 kDa.
Western blot testing of human liver lysate with Transthyretin antibody. Predicted molecular weight ~16 kDa.
IHC staining of FFPE human liver with Transthyretin antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+1
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Transthyretin antibody. These results demonstrate the foremost specificity of the TTR/4296 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Transthyretin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Transthyretin antibody is available for research use only.
Regulatory & Compliance
Badge
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