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OX40 Antibody / CD134
SKU / CAT#: V8563-100UG
$49900
usd
$4.99/UG
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V8563-100UG

OX40 Antibody / CD134

NSJ Bioreagents
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SKU / CAT#: V8563-100UG
MPN: V8563-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
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Description
This MAb recognizes a protein of 43kDa, identified as OX40, which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand / TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid...
This MAb recognizes a protein of 43kDa, identified as OX40, which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand / TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the OX40 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This OX40 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
JrqiBox40-antibody-ox40-3427-v8563
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P43489
CLONE NUMBER
OX40/3427
*USAGE / SAFETY STATEMENT
This OX40 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
ELISA, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2c, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A portion of amino acids 59-205 from the human protein was used as the immunogen for the OX40 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
ELISA: order Ab without BSA for coating,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the OX40 antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic, membranous
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human tonsil with OX40 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human tonsil with OX40 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human tonsil with OX40 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using OX40 antibody. These results demonstrate the foremost specificity of the OX40/3427 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the OX40 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This OX40 antibody is available for research use only.
Regulatory & Compliance
Badge
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