CD40 Antibody
SKU / CAT#: V8350-100UG
$49900
usd$4.99/UG
CD40 Antibody
NSJ BioreagentsSKU / CAT#: V8350-100UG
MPN: V8350-100UG
$49900
usd$4.99/UG
Available
SHIPS Jul 4th
Available
SHIPS Jul 4th
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Description
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can...
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CD40 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CD40 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P27512CLONE NUMBER
FGK45.5
*USAGE / SAFETY STATEMENT
This CD40 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
Functional Studies, FACS, IF
HOST SPECIES
Rat
ISOTYPE
Rat IgG2a, kappa
REACTIVITY SPECIES
Mouse
CLONALITY
Monoclonal (rat origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Purified recombinant Mouse CD40 fusion protein was used as the immunogen for the CD40 antibody.
STORAGE BUFFER
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Functional Studies (order BSA/azide-free format),Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CD40 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CD40 antibody is available for research use only.
Regulatory & Compliance
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