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TOP1MT Antibody / Topoisomerase I mitochondrial
SKU / CAT#: V8148SAF-100UG
$49900
usd
$4.99/UG
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V8148SAF-100UG

TOP1MT Antibody / Topoisomerase I mitochondrial

NSJ Bioreagents
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SKU / CAT#: V8148SAF-100UG
MPN: V8148SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium,...
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium,...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TOP1MT antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TOP1MT antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
LcGXPtop1mt-antibody-top1mt-613-v8148
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q969P6
CLONE NUMBER
TOP1MT/613
*USAGE / SAFETY STATEMENT
This TOP1MT antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
WB, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Recombinant full-length human TOP1MT protein was used as the immunogen for the TOP1MT antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the TOP1MT antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic (Mitochondria)
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human melanoma with TOP1MT antibody (clone TOP1MT/613). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human melanoma with TOP1MT antibody (clone TOP1MT/613). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human melanoma with TOP1MT antibody (clone TOP1MT/613). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+2
IHC staining of FFPE human gallbladder with TOP1MT antibody (clone TOP1MT/613). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TOP1MT antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TOP1MT antibody is available for research use only.
Regulatory & Compliance
Badge
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