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p73 Antibody / Tumor Protein 73
SKU / CAT#: V8089SAF-100UG
$49900
usd
$4.99/UG
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  4. p73 Antibody / Tumor Protein 73
V8089SAF-100UG

p73 Antibody / Tumor Protein 73

NSJ Bioreagents
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SKU / CAT#: V8089SAF-100UG
MPN: V8089SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 1st
Available
SHIPS Jul 1st
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Description
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the p73 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This p73 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
WYhKYp73-antibody-p73-2531-v8089
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
O15350
CLONE NUMBER
P73/2531
*USAGE / SAFETY STATEMENT
This p73 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A recombinant full-length human protein was used as the immunogen for this p73 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
LOCALIZATION
Nuclear
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human skin with p73 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human skin with p73 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free p73 antibody as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the p73 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This p73 antibody is available for research use only.
Regulatory & Compliance
Badge
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