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Insulin Receptor alpha Antibody
SKU / CAT#: V8071SAF-100UG
$49900
usd
$4.99/UG
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V8071SAF-100UG

Insulin Receptor alpha Antibody

NSJ Bioreagents
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SKU / CAT#: V8071SAF-100UG
MPN: V8071SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
SKU
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Description
The insulin receptor (INSR) is a heterodimeric protein complex that has an intracellular subunit, which is disulfide-linked to a transmembrane segment. The insulin ligand binds to the INSR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to INSR induces phosphorylation of intra-cellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Type 1 diabetes is an autoimmune condition of the endocrine pancreas...
The insulin receptor (INSR) is a heterodimeric protein complex that has an intracellular subunit, which is disulfide-linked to a transmembrane segment. The insulin ligand binds to the INSR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to INSR induces phosphorylation of intra-cellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Type 1 diabetes is an autoimmune condition of the endocrine pancreas...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Insulin Receptor alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Insulin Receptor alpha antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
kcGFlinsulin-receptor-alpha-antibody-insr-1661-v8071
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P06213
CLONE NUMBER
INSR/1661
*USAGE / SAFETY STATEMENT
This Insulin Receptor alpha antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
ELISA
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A recombinant fragment from the extracellular domain of human Insulin Receptor alpha was used as the immunogen for this Insulin Receptor alpha antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
ELISA (order BSA-free format for coating)
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
Questions & Answers (0)
Citations (0)
SDS-PAGE analysis of purified, BSA-free Insulin Receptor alpha antibody (clone INSR/1661) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free Insulin Receptor alpha antibody (clone INSR/1661) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Insulin Receptor alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Insulin Receptor alpha antibody is available for research use only.
Regulatory & Compliance
Badge
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