SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq]

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Store the SOX10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Safety Statement

This SOX10 antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

pnPrLsox10-antibody-protein-microarray-validated-sxb10-1-v3508

Specifications

CLASS

Primary Antibodies

SUBCLASS

Monoclonal

UNIPROT ID

P56693

CLONE NUMBER

SBX10-1

*USAGE / SAFETY STATEMENT

This SOX10 antibody is available for research use only.

FORMAT

Purified

APPLICATION.1

WB, IHC-P

HOST SPECIES

Mouse

ISOTYPE

Mouse IgG2b, kappa

REACTIVITY SPECIES

Human

CLONALITY

Monoclonal (mouse origin)

PURIFICATION

Protein G affinity chromatography

IMMUNOGEN

Amino acids 115-269 of the human protein were used as the immunogen for the SOX10 antibody.

STORAGE BUFFER

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

APPLICATION DETAILS

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

APPLICATION NOTES

Titering of the SOX10 antibody may be required for optimal performance.<p>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

LOCALIZATION

Nuclear