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SOX10 Antibody
SKU / CAT#: V3508-100UG
$49900
usd
$4.99/UG
V3508-100UG

SOX10 Antibody

NSJ Bioreagents
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SKU / CAT#: V3508-100UG
MPN: V3508-100UG
$49900
usd
$4.99/UG
Available
SHIPS Mar 21st
Available
SHIPS Mar 21st
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Description
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq]
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the SOX10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SOX10 antibody is available for research use only.
Regulatory & Compliance
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Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P56693
CLONE NUMBER
SBX10-1
*USAGE / SAFETY STATEMENT
This SOX10 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Amino acids 115-269 of the human protein were used as the immunogen for the SOX10 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
APPLICATION DETAILS
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
APPLICATION NOTES
Titering of the SOX10 antibody may be required for optimal performance.<p>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
LOCALIZATION
Nuclear
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Citations (0)
Protein array validation of the SOX10 antibody: Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SOX10 antibody (clone SBX10-1). These results demonstrate the foremost specificity of the SBX10-1 mAb.<P><P>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Protein array validation of the SOX10 antibody: Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SOX10 antibody (clone SBX10-1). These results demonstrate the foremost specificity of the SBX10-1 mAb.<P><P>Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody. Predicted molecular weight ~50 kDa.
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1). Required HIER: boil sections in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the SOX10 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SOX10 antibody is available for research use only.
Regulatory & Compliance
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