TRP1 / Tyrosinase-Related Protein-1 Antibody
SKU / CAT#: V3174-20UG
$21900
usd$10.95/UG
TRP1 / Tyrosinase-Related Protein-1 Antibody
NSJ BioreagentsSKU / CAT#: V3174-20UG
MPN: V3174-20UG
$21900
usd$10.95/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TRP1 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P17643CLONE NUMBER
TA99
*USAGE / SAFETY STATEMENT
This TRP1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF, IHC-F
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a, kappa
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
SK-MEL-23 cells were used as the immunogen for this TRP1 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 1-2ug/ml for 30 min at RT
APPLICATION NOTES
The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.
LOCALIZATION
Cytoplasmic
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TRP1 antibody is available for research use only.
Regulatory & Compliance
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