Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
COUNTRY OF ORIGIN
China
GENE ID
https://www.ncbi.nlm.nih.gov/gene/23451
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
MWCO (kDa)
16kDa/145kDa
SOURCE
Rabbit
ANTIBODY TYPE
Polyclonal Antibodies
ISOTYPE
IgG
PURIFICATION
Affinity purification
IMMUNOGEN
Recombinant protein of human SF3B1 (NP_001005526.1).
SWISS-PROT NO.
O75533
BACKGROUND
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
RECOMMENDED DILUTIONS
WB 1:500 - 1:2000
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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