Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
COUNTRY OF ORIGIN
China
GENE ID
https://www.ncbi.nlm.nih.gov/gene/5832
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
MWCO (kDa)
87kDa
SOURCE
Rabbit
ANTIBODY TYPE
Polyclonal Antibodies
ISOTYPE
IgG
PURIFICATION
Affinity purification
IMMUNOGEN
Recombinant protein of human ALDH18A1 (NP_002851.2).
SWISS-PROT NO.
P54886
BACKGROUND
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
RECOMMENDED DILUTIONS
WB 1:500 - 1:2000
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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