Specifications
GENE ID
https://www.ncbi.nlm.nih.gov/gene/80031;
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURIFICATION
Antigen affinity purification.
IMMUNOGEN
Synthetic peptide corresponding to residues near the N terminal of human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SPECIFICITY
The antibody detects endogenous levels of total SEMA6D protein.
BACKGROUND
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies.
ALTERNAME
FLJ11598; KIAA1479; SEM6D; SEMA6D; Semaphorin-6D
FORM OF ANTIBODY
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
RECOMMENDED DILUTIONS
Immunohistochemistry: 1:25-1:100
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