CCNF Antibody

China

https://www.ncbi.nlm.nih.gov/gene/899;

For laboratory research and development purposes only.

88kd

WB IHC

Polyclonal

Rabbit

Hu

Antigen affinity purification.

CCNF

Fusion protein corresponding to residues near the C terminal of human cyclin F

The antibody detects endogenous levels of total CCNF protein.

P41002

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

FBX1; FBXO1

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Western blotting: 1:200-1:1000<br/>Immunohistochemistry: 1:25-1:100