MARK3 Antibody

China

https://www.ncbi.nlm.nih.gov/gene/4140;

For laboratory research and development purposes only.

85kd

WB IHC

Polyclonal

Rabbit

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

MARK3

Synthesized peptide derived from N-terminal of human MARK3.

The antibody detects endogenous levels of total MARK3 protein.

P27448

Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.<br/><br/>Peng C.Y., Cell Growth Differ. 9:197-208(1998).<br/>Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).<br/>Wissing J., Mol. Cell. Proteomics 6:537-547(2007)

C-TAK1; Cdc25C- associated protein kinase 1; EC 2.7.11.1; MAP/microtubule affinity-regulating kinase 3; Protein kinase STK10

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Western blotting: 1:500~1:3000<br/>Immunohistochemistry: 1:50~1:100<br/>