(±)-O-Desmethyl venlafaxine is the active metabolite of venlafaxine (Item No. 11567), an inhibitor of the reuptake of both serotonin and norepinephrine. Venlafaxine is metabolized by cytochrome P450 2D6, yielding O-desmethyl venlafaxine, which is pharmacologically similar to the parent drug. (±)-O-Desmethyl venlafaxine inhibits the human serotonin and norepinephrine transporters with IC50 values of 47.3 and 531.3 nM, respectively.
(±)-O-Desmethyl venlafaxine is the active metabolite of venlafaxine (Item No. 11567), an inhibitor of the reuptake of both serotonin and norepinephrine. Venlafaxine is metabolized by cytochrome P450 2D6, yielding O-desmethyl venlafaxine, which is pharmacologically similar to the parent drug. (±)-O-Desmethyl venlafaxine inhibits the human serotonin and norepinephrine transporters with IC50 values of 47.3 and 531.3 nM, respectively.
Shipping & Handling
Shipped In
Wet ice in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.