Rosmanol is a polyphenol that has been found in R. officinalis and has diverse biological activities. It is an inhibitor of α-glucosidase and α-amylase (IC50s = 16.4 and 40.9 µg/ml, respectively) and has antioxidant activity in a Trolox equivalent absorbance capacity (TEAC) assay. Rosmanol activates the mitochondrial and death receptor apoptosis pathways and induces apoptosis in COLO 205 colorectal cancer cells (IC50 = ~42 µM). It also inhibits LPS-induced production of prostaglandin E2 (PGE2), as well as reduces the activity of NF-κB, inducible nitric oxide synthase (iNOS), and COX-2 induced...
Rosmanol is a polyphenol that has been found in R. officinalis and has diverse biological activities. It is an inhibitor of α-glucosidase and α-amylase (IC50s = 16.4 and 40.9 µg/ml, respectively) and has antioxidant activity in a Trolox equivalent absorbance capacity (TEAC) assay. Rosmanol activates the mitochondrial and death receptor apoptosis pathways and induces apoptosis in COLO 205 colorectal cancer cells (IC50 = ~42 µM). It also inhibits LPS-induced production of prostaglandin E2 (PGE2), as well as reduces the activity of NF-κB, inducible nitric oxide synthase (iNOS), and COX-2 induced...
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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