15(R)-HETE is a monohydroxy fatty acid. It is produced by aspirin-acetylated COX-2 from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) and converted into the specialized pro-resolving mediator 15(R)-lipoxin A4 (Item No. 90415) and 15(R)-lipoxin B4 in a transcellular process via 5-lipoxygenase (5-LO). It is also produced by the cytochrome P450 (CYP) isoform CYP2C9. 15(R)-HETE can also be formed from arachidonic acid by COX-1 in stimulated human mast cells and accumulates because, unlike 15(S)-HETE (Item No. 34720), it is not converted to 15-KETE (15-OxoETE; Item No. 34730) by 15-hydroxyprostaglandin...
15(R)-HETE is a monohydroxy fatty acid. It is produced by aspirin-acetylated COX-2 from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) and converted into the specialized pro-resolving mediator 15(R)-lipoxin A4 (Item No. 90415) and 15(R)-lipoxin B4 in a transcellular process via 5-lipoxygenase (5-LO). It is also produced by the cytochrome P450 (CYP) isoform CYP2C9. 15(R)-HETE can also be formed from arachidonic acid by COX-1 in stimulated human mast cells and accumulates because, unlike 15(S)-HETE (Item No. 34720), it is not converted to 15-KETE (15-OxoETE; Item No. 34730) by 15-hydroxyprostaglandin...
Shipping & Handling
Shipped In
Wet ice in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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