Byakangelicol is a furanocoumarin that has been found in A. dahurica and has diverse biological activities. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 46.3 and 45.2 µM, respectively). Byakangelicol inhibits LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50 = 16.9 µg/ml) and IL-1β-induced COX-2 activity and prostaglandin E2 (PGE2) release in A549 cells when used at concentrations ranging from 10 to 50 µM. It also reduces cytotoxicity induced by tacrine (Item No. 70240) in HepG2 cells (EC50 = 36.6 µM).
Byakangelicol is a furanocoumarin that has been found in A. dahurica and has diverse biological activities. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 46.3 and 45.2 µM, respectively). Byakangelicol inhibits LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50 = 16.9 µg/ml) and IL-1β-induced COX-2 activity and prostaglandin E2 (PGE2) release in A549 cells when used at concentrations ranging from 10 to 50 µM. It also reduces cytotoxicity induced by tacrine (Item No. 70240) in HepG2 cells (EC50 = 36.6 µM).
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Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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