Daclatasvir-d6 is intended for use as an internal standard for the quantification of daclatasvir (Item No. 23730) by GC- or LC-MS. Daclatasvir is a first generation direct-acting inhibitor of hepatitis C virus (HCV) non-structural protein 5A (NS5A; Kds = 8 and 210 nM for the NS5A33-202 and NS5A26-202 residues of HCV genotype 1b, respectively). It potently inhibits HCV replication in multiple HCV replicon genotypes (EC50s = 9-146 pM) with the highest potency in genotypes 1b and 4a (EC50s = 9 and 12 pM, respectively). Daclatasvir disrupts the subcellular localization of NS5A in Huh7.5 cells and...

Shipping & Handling

Shipped In

Room Temperature in continental US; may vary elsewhere

Safety & Storage

Storage Temperature

-20°C

Safety Statement

WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Regulatory & Compliance

Technical Documents

Datasheet (1)

AAXNc29077.pdf

MSDS (1)

DDwTa29077m.pdf

Questions & Answers (0)

Citations (0)

Shipping & Handling

Shipped In

Room Temperature in continental US; may vary elsewhere

Safety & Storage

Storage Temperature

-20°C

Safety Statement

WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Regulatory & Compliance

We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.

Join BETA

Join Our List

Subscribe to the Scoop blog and get the latest updates on life in the lab.