The Gr-1 antigen is a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported.
Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Westen Blot. Reported to deplete mouse mature...
The Gr-1 antigen is a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported.
Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Westen Blot. Reported to deplete mouse mature...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
SUBCLASS
Cell Markers
APPLICATION
FC IHC IP WB
CLONE NUMBER
RB6-8C5
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein G affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
GRADE
Affinity Purified
ANTIBODY TYPE
Mab
HOST SPECIES
mouse
ISOTYPE
IgG2b
CROSS REACTIVITY
Mo
IMMUNOGEN
Normal murine bone marrow cells.
SPECIFIC ACTIVITY
Recognizes mouse Gr-1 antigen. Reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated.
COMMODITY CODE
30021010
HOST
rat
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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