PKP4 (p0071, Plakophilin 4, Catenin 4)

p0071 is specific for a subtype of adherens junctions, with a molecular mass of 135kD and is closely related to neurojungin/delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4. Applications: Suitable for use in Immunofluorescence, Immunocytochemistry, Immunohistochemistry...