NGFR p75 (Tumor Necrosis Factor Receptor Superfamily Member 16, Gp80-LNGFR, Low affinity neurotrophin Receptor p75NTR, Low-affinity nerve Growth Factor Receptor, NGF Receptor, p75 ICD, CD271, NGFR, TNFRSF16)

NGFR p75 is a 75kD transmembrane glycoprotein (399 a.a.) consisting of an extracellular domain (222 a.a.) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22 a.a.), and a cytoplasmic domain (155 a.a.). NGFR p75 is mainly expressed in Schwann cells and neurons and in a variety of non neuronal cells. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended...