1%BSA in PBS Sterile

Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars. AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer’s disease, cataract, and aging. AGE receptors, such as the receptor for AGE (RAGE), mediate biological responses to AGEs, including endocytic uptake and degradation and induction of cytokines and growth factors.