Tetracycline

Antibiotics

Antibiotics (Chemical Structure Class)

Japan

DNA aptamer research Reference Single-stranded DNA aptamers specific for antibiotics tetracyclines J.H. Niazi, S.J. Lee, M.B. Gu, Bioorg. Med. Chem. 2008, 16, 7245 Application Tetracycline: a Broad Spectrum Polyketide Antibiotic and a Selective Reagent Genetically Engineered Cells Tetracycline is a polyketide antibiotic isolated from Streptomyces genus. Tetracycline has broad activity against Gram-negative bacteria and Gram-positive bacteria, with a few exceptions, such as Pseudomonas aeruginosa and Proteus species. Tetracycline inhibits protein synthesis in susceptible organisms by binding to the A-site on the 50S subunit of a bacterial ribosome. However, tetracycline-resistant bacterial strains appeared soon after its introduction. Tetracycline is used in molecular biology as a selective reagent most commonly to isolate bacteria coupled to a gene coding for tetracycline resistance, which is one of the most frequently used selection markers for obtaining transgenic cells. Recently, tetracycline is used for tetracycline-controlled transcriptional activation systems in cells. (The product is for research purpose only.)

MFCD00151232

468593045.0

2230417.0

GHS07

Warning

H302 : Harmful if swallowed.

P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.

QI8750000

9196.0

For laboratory research and development purposes only.

>95.0%(T)(HPLC)

Solid

444.44

Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).

Light yellow to Yellow powder to crystal

C22H24N2O8

min. 95.0 area%

2941.30.0000

>95.0%(T)(HPLC)