Salicin: An Alcoholic β-Glucoside Derived from Willow Bark with Anti-Inflammatory Activity
Salicin is an alcoholic β-glucoside derived from willow bark which has been traditionally used as an anti-inflammatory, antipyretic, and analgesic medicine.1,2) Salicin acts as a non-selective COX inhibitor, and effects very similar to acetylsalicylic acid [A2262].3) Recently, various studies have demonstrated that the anti-inflammatory activity of willow bark extract is associated with down regulation of the inflammatory mediators tumor necrosis factor-α and nuclear factor-kappa B.2) In addition, some studies have been reported that salicin acts as an agonist on the bitter taste receptor, TAS2R16.4) (The product is for research purpose only.)
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