Specifications
CLASS
Pharmaceutical Ingredients (for Research and Experimental Use)
SUBCLASS
Antifungal Ingredients (for Research and Experimental Use)
APPLICATION
Liranaftate: A Synthetic Thiocarbamate Antifungal Reagent
Liranaftate (piritetrate or M-732) is a chemical synthetic antifungal reagent, belonging chemically to the thiocarbamates. Although the exact mechanism of action is not entirely known, liranaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane. Similar antifungal reagent includes tolnaftate [T3059]. (The product is for research purpose only.)
PUBCHEM SUBSTANCE ID
354335085.0
BEILSTEIN/REAXYS NUMBER
12615149.0
HAZARD STATEMENTS
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H317 : May cause an allergic skin reaction.
PRECAUTIONARY STATEMENTS
P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P272 : Contaminated work clothing must not be allowed out of the workplace.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
White to Almost white powder to crystal
MOLECULAR FORMULA
C18H20N2O2S
PURITY (HPLC)
min. 98.0 area%
PURITY / ANALYSIS METHOD
>98.0%(HPLC)
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