Bis(hexafluoroacetylacetonato)copper(II)

C-H Activation [Catalysis]

Copper Compounds [C-H Activation]

Japan

Copper-catalyzed Cyclopropanation of alpha-Diazoketones to Norcaradienes Typical procedure (entry 4): A microwave reaction vessel is charged with a solution of the diazoketone (53 mg) in CH2Cl2 (10 mL). Cu(hfacac)2 (9.5 mg) in CH2Cl2 (2 mL) is added via syringe. The vial is placed in the microwave reactor and heated to 120 °C for 1 minute (ramp from 22 °C to 120 °C requires 2 min). The solvent is removed under reduced pressure, and the residue is purified by flash chromatography (eluent: 0 to 100 % EtOAc/hexanes) to give the norcaradiene (30mg, 64 %) as a white solid.

MFCD00064754

87570941.0

GHS07

Warning

H315 : Causes skin irritation. H319 : Causes serious eye irritation.

P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse.

For laboratory research and development purposes only.

>95.0%(T)

Solid

477.65

Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).

Green to Dark green powder to crystal

C10H2CuF12O4

2931.90.9051

>95.0%(T)