Specifications
CLASS
Pharmaceutical Ingredients (for Research and Experimental Use)
SUBCLASS
Antifungal Ingredients (for Research and Experimental Use)
APPLICATION
Ferrostatin-1: A Potent and Selective Inhibitor of Ferroptosis
Ferrostatin-1 is a potent and selective inhibitor of ferroptosis which is a form of regulated, oxidative, non-apoptotic cell death. Ferroptosis is characterized by iron-dependent accumulation of reactive oxygen species in lipids and depletion of polyunsaturated fatty acids in cell membranes.1,2) Ferroptosis can be triggered by small molecules or conditions that inhibit glutathione biosynthesis or the glutathione-dependent antioxidant enzyme glutathione peroxidase 4 (GPX4).3,4) (The product is for research purpose only.)
PUBCHEM SUBSTANCE ID
468591907.0
BEILSTEIN/REAXYS NUMBER
9413226.0
HAZARD STATEMENTS
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
PRECAUTIONARY STATEMENTS
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
White to Amber to Dark purple powder to crystal
MOLECULAR FORMULA
C15H22N2O2
PURITY (HPLC)
min. 98.0 area%
PURITY / ANALYSIS METHOD
>98.0%(HPLC)
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