Tetramethyl-1,3-cyclobutanedione [Precursor to Dimethyl Ketene]

Non-Heterocyclic Building Blocks

Carbonyl Compounds [Non-Heterocyclic Building Blocks]

Japan

Preparation of Dimethyl Ketene Typical Procedure: Tetramethyl-1,3-cyclobutanedione is placed in the ketene generation apparatus, heated at 120 ℃, and sublimed, then thermally decomposed by means of the red heated Nichrome wire under the nitrogen atmosphere. Subsequently, the evolved gas is captured by means of a trap cooled in dry ice-acetone to obtain dimethylketene in about 60% yield. Dimethylketene is a yellowish liquid (bp 34 ℃) with characteristic odor, remarkable reactivity, and transforms into a solid dimer when allowed to stand at room temperature. On exposure to air it generates white solid peroxides and explodes with even the slightest stimulus. For this reason, its monomer is stored under nitrogen at -78 ℃ and it is used immediately.

MFCD00001331

87566962.0

1072094.0

GU1775000

For laboratory research and development purposes only.

>99.0%(GC)

Solid

140.18

Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).

White to Almost white powder to crystal

C8H12O2

738.0

2914.19.0000

>99.0%(GC)