Specifications
CLASS
Pharmaceutical Ingredients (for Research and Experimental Use)
SUBCLASS
Antidiabetic Ingredients (for Research and Experimental Use)
APPLICATION
Buformin Hydrochloride: A Biganide Antidiabetic
Buformin hydrochloride is a biganide antidiabetic such as metformin [M2009] and phenformin. They delay absorption of glucose from the gastrointestinal tract, increase insulin sensitivity and glucose uptake into cells, and inhibits synthesis of glucose by the liver.1) Although, buformin and phenformin were withdrawn from the clinical market in many countries due to an elevated risk of causing lactic acidosis which is a condition characterized by overproduction of lactic acid.2,3) Meanwhile, it has been reported that biganide antidiabetics inhibit the growth and development of cancer.4,5) (The product is for research purpose only.)
PUBCHEM SUBSTANCE ID
468590843.0
BEILSTEIN/REAXYS NUMBER
3627999.0
HAZARD STATEMENTS
H302 : Harmful if swallowed.
H315 + H320 : Causes skin and eye irritation.
PRECAUTIONARY STATEMENTS
P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
White to Light yellow to Light orange powder to crystal
MOLECULAR FORMULA
C6H15N5·HCl
PURITY (HPLC)
min. 95.0 area%
PURITY / ANALYSIS METHOD
>95.0%(HPLC)
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