Specifications
CLASS
Immune System, Inflammation, Allergy Research
SUBCLASS
Histamine Receptor Antagonists
APPLICATION
Bilastine: A Selective Histamine H1 Receptor Antagonist
Bilastine is a selective histamine H1 receptor antagonist. On the other hand, the results of studies on bilastine confirmed the lack of significant antagonism against not only histamine H2 and H3 receptors but also serotonin, bradykinin, leukotriene D4, calcium, muscarinic M3-receptors, α1-adrenoceptors, and β2-adrenoceptors. Furthermore, bilastine do not cause sedation or interact with cytochrome P 450. Therefore, bilastine is used as a second generation H1-antihistamine for the treatment of allergic rhinitis and chronic urticarial. For your reference, [P2382] is a synthetic intermediate of bilastine.(The product is for research purpose only.)
PUBCHEM SUBSTANCE ID
354335500.0
BEILSTEIN/REAXYS NUMBER
13851185.0
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
White to Light yellow powder to crystal
MOLECULAR FORMULA
C28H37N3O3
PURITY (HPLC)
min. 98.0 area%
PURITY / ANALYSIS METHOD
>98.0%(T)(HPLC)
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