Bis(acetonitrile)palladium(II) Dichloride

C-H Activation [Catalysis]

Palladium Compounds [C-H Activation]

Japan

Synthesis of Oxindoles Typical Procedure: To a dried screw-cap vial is added anilide (0.3 mmol), AgOCOCF3 (132.5 mg, 0.6 mmol), (CH3CN)2PdCl2 (3.5 mg, 0.015 mmol) and chlorobenzene. The reaction mixture is stirred at 100-120 °C for 3-12 h in a pre-heated oil bath. After cooling to room temperature, the reaction is diluted with EtOAc and filtered with a glass filter. The filtrate is washed with 5% aqueous NaHCO3 and brine. The extract is dried over MgSO4 and concentrated in vacuo. The crude is purified by preparative TLC.

MFCD00013122

87564577.0

14640205.0

GHS06

Danger

H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled.

P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P362 : Take off contaminated clothing and wash before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up.

6.1

III

UN3439

For laboratory research and development purposes only.

>98.0%(T)

Solid

259.43

Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).

Light yellow to Brown powder to crystaline

C4H6Cl2N2Pd

17192.0

2931.90.9051

>98.0%(T)