Specifications
CLASS
Basic Dyes [Chemistry]
APPLICATION
Efflux pump inhibitor
Berberine can potentially inhibit a diverse range of different efflux pumps, including the resistance nodulation division (RND) family. 1,2)
Berberine Sulfate: An Isoquinoline Alkaloid with Multispectrum Activities
Berberine sulfate is an isoquinoline alkaloid extracted from many plants as with berberine chloride [B0450], another formulation. Recent pharmacological studies on berberine sulfate have revealed its various pharmacological activities, including antimicrobial1) and antineoplastic properties2). In addition, a comparative study of the dissolution properties of berberine in hydrochloride, sulfate and iodide salts has been reported3). (The product is for research purpose only.)
PUBCHEM SUBSTANCE ID
87563488.0
BEILSTEIN/REAXYS NUMBER
3877732.0
HAZARD STATEMENTS
H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled.
PRECAUTIONARY STATEMENTS
P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell.
P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
Light yellow to Yellow powder to crystal
MOLECULAR FORMULA
C40H36N2O12S
SDBS (AIST SPECTRAL DB)
5030.0
PURITY (HPLC)
min. 98.0 area%
FULL NOTE
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
PURITY / ANALYSIS METHOD
>98.0%(T)(HPLC)
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