The CPA1 gene encodes Carboxypeptidase A1, a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [RefSeq]

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Store the Carboxypeptidase A1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Safety Statement

This Carboxypeptidase A1 antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

geGeCcarboxypeptidase-a1-antibody-cbpa1-1-v7433

Specifications

CLASS

Primary Antibodies

SUBCLASS

Monoclonal

UNIPROT ID

P15085

CLONE NUMBER

CBPA1-1

*USAGE / SAFETY STATEMENT

This Carboxypeptidase A1 antibody is available for research use only.

FORMAT

Purified

APPLICATION.1

IHC-P

HOST SPECIES

Mouse

ISOTYPE

Mouse IgG1, kappa

REACTIVITY SPECIES

Human

CLONALITY

Monoclonal (mouse origin)

PURIFICATION

Protein G affinity

IMMUNOGEN

Full length recombinant human protein was used as the immunogen for the Carboxypeptidase A1 antibody.

STORAGE BUFFER

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

APPLICATION DETAILS

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

APPLICATION NOTES

Optimal dilution of the Carboxypeptidase A1 antibody should be determined by the researcher.<br><br>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

LOCALIZATION

Cytoplasmic, secreted