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CD44v3 Antibody
SKU / CAT#: V3768-20UG
$21900
usd
$10.95/UG
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V3768-20UG

CD44v3 Antibody

NSJ Bioreagents
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SKU / CAT#: V3768-20UG
MPN: V3768-20UG
$21900
usd
$10.95/UG
Available
SHIPS Apr 7th
Available
SHIPS Apr 7th
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Description
This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis...
This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CD44v3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CD44v3 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
LCLIWcd44v3-antibody-3g5-v3768
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This CD44v3 antibody is available for research use only.
FORMAT
Purified
SUBCLASS
Monoclonal
UNIPROT ID
P16070
CLONE NUMBER
3G5
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
An amino acid sequence from the variant 3 domain of CD44 was used as the immunogen for the CD44v3 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
APPLICATION NOTES
Titering of the CD44v3 antibody may be required for optimal performance.
LOCALIZATION
Cell surface, cytoplasmic
Questions & Answers (0)
Citations (0)
IHC testing of FFPE human cervical carcinoma with CD44v3 antibody (clone 3G5). Required HIER: steam sections in pH 9 10mM Tris with 1mM EDTA buffer for 10-20 min and allow to cool before testing.
IHC testing of FFPE human cervical carcinoma with CD44v3 antibody (clone 3G5). Required HIER: steam sections in pH 9 10mM Tris with 1mM EDTA buffer for 10-20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free CD44v3 antibody (clone 3G5) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CD44v3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CD44v3 antibody is available for research use only.
Regulatory & Compliance
Badge
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