This antibody recognizes a protein of 185kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
This antibody recognizes a protein of 185kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Shipping & Handling
Shipped In
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Safety & Storage
Storage Temperature
Store the ErbB2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This ErbB2 antibody is available for research use only.
This ErbB2 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
ELISA, FACS, IF
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a, kappa
REACTIVITY SPECIES
Human, Rat
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G purified
IMMUNOGEN
Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
ELISA (order BSA/sodium azide-free format for coating),Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml
APPLICATION NOTES
Variations in protocols, secondaries and substrates may require the antibody to be titered for optimal performance.<p>1. This ErbB2 antibody binds to the extracellular/cell surface region of the protein.
LOCALIZATION
Extracellular/Intracellular cell membrane
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the ErbB2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This ErbB2 antibody is available for research use only.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.