The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation...
The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation...
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Safety & Storage
Storage Temperature
After reconstitution, the EPO Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Safety Statement
This EPO Receptor antibody is available for research use only.
A recombinant human partial protein corresponding to amino acids E48-E226 was used as the immunogen for the EPO Receptor antibody.
STORAGE BUFFER
0.5mg/ml if reconstituted with 0.2ml sterile DI water
APPLICATION DETAILS
Western Blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
APPLICATION NOTES
Optimal dilution of the EPO Receptor antibody should be determined by the researcher.
BUFFER
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
After reconstitution, the EPO Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Safety Statement
This EPO Receptor antibody is available for research use only.
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