FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Aliquot the FGG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Safety Statement

This FGG antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

zfldbfgg-antibody-fibrinogen-gamma-chain-f54860

Specifications

CLASS

Primary Antibodies

SUBCLASS

Polyclonal

UNIPROT ID

P02679

*USAGE / SAFETY STATEMENT

This FGG antibody is available for research use only.

FORMAT

Purified

APPLICATION.1

IHC-P, IF, WB

HOST SPECIES

Rabbit

ISOTYPE

Rabbit Ig

REACTIVITY SPECIES

Human

CLONALITY

Polyclonal (rabbit origin)

PURIFICATION

Purified

IMMUNOGEN

A portion of amino acids 420-449 from the human protein was used as the immunogen for the FGG antibody.

STORAGE BUFFER

In 1X PBS, pH 7.4, with 0.09% sodium azide

APPLICATION DETAILS

Immunohistochemistry (FFPE): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:500-1:1000

APPLICATION NOTES

The stated application concentrations are suggested starting points. Titration of the FGG antibody may be required due to differences in protocols and secondary/substrate sensitivity.