UBE1 / UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
UBE1 / UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding the same protein, but with different 5' UTR.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Ubiquitin-like modifier-activating enzyme 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Ubiquitin-like modifier-activating enzyme 1 antibody is available for research use only.
This Ubiquitin-like modifier-activating enzyme 1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P, WB
HOST SPECIES
Rabbit
ISOTYPE
Rabbit Ig
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
Purified
IMMUNOGEN
A portion of amino acids 1026-1058 from the human protein was used as the immunogen for the Ubiquitin-like modifier-activating enzyme 1 antibody.
STORAGE BUFFER
In 1X PBS, pH 7.4, with 0.09% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1:25, Western blot: 1:500-1:2000
APPLICATION NOTES
The stated application concentrations are suggested starting points. Titration of the Ubiquitin-like modifier-activating enzyme 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
LOCALIZATION
Cytoplasmic, nuclear
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Ubiquitin-like modifier-activating enzyme 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Ubiquitin-like modifier-activating enzyme 1 antibody is available for research use only.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.