The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family,...

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Aliquot the PSMA5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Safety Statement

This PSMA5 antibody is available for research use only.

Regulatory & Compliance

Specifications

CLASS

Primary Antibodies

SUBCLASS

Monoclonal

UNIPROT ID

P28066

CLONE NUMBER

426CT8.5.1

*USAGE / SAFETY STATEMENT

This PSMA5 antibody is available for research use only.

FORMAT

Purified

APPLICATION.1

WB, IF, IHC-P

HOST SPECIES

Mouse

ISOTYPE

IgG1

REACTIVITY SPECIES

Human, Mouse, Rat

CLONALITY

Monoclonal (mouse origin)

PURIFICATION

Protein G affinity

IMMUNOGEN

Recombinant human protein was used as the immunogen for the PSMA5 antibody.

STORAGE BUFFER

In 1X PBS, pH 7.4, with 0.09% sodium azide

APPLICATION DETAILS

Western blot: 1:500-1:2000, Immunofluorescence: 1:25, Immunohistochemistry (FFPE): 1:25

APPLICATION NOTES

The stated application concentrations are suggested starting points. Titration of the PSMA5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

LOCALIZATION

Cytoplasmic, nuclear