ZWINT is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
ZWINT is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the ZWINT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This ZWINT antibody is available for research use only.
This ZWINT antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB, FACS, IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit Ig
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
SAS precipitation
IMMUNOGEN
A portion of amino acids 59-88 from the human protein was used as the immunogen for the ZWINT antibody.
STORAGE BUFFER
In 1X PBS, pH 7.4, with 0.09% sodium azide
APPLICATION DETAILS
Western blot: 1:500-1:2000,Flow cytometry: 1:25 (1x10e6 cells),Immunohistochemistry (FFPE): 1:25
APPLICATION NOTES
The stated application concentrations are suggested starting points. Titration of the ZWINT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the ZWINT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This ZWINT antibody is available for research use only.
Regulatory & Compliance
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