This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Safety & Storage
Storage Temperature
Aliquot the Complement factor H antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Complement factor H antibody is available for research use only.
The stated application concentrations are suggested starting points. Titration of the Complement factor H antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Complement factor H antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Complement factor H antibody is available for research use only.
Regulatory & Compliance
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